Multiple emails does it require any customization?

I just set up my usb with Thunderbird Mail and am trying to run two seperate email accounts on the one application. I have the first one set up and it runs perfectly. When I have the second one set up I get two messages...
first....Sending of username did not succeed when I click ok it goes away then I get Sending of password did not succeed and asks to retype my password. Back into the loop I go. I know it works and double and triple checked everything. When set up in Outlook express and did a test no problems.

My question is do I need any custo settings in the profile or ? to run two profiles at the same time?

Thanks

Pj