can't work with RamDisk

I move the sysytem TEMP(TMP) folder to the RamDisk (R:\)
Then ClamWinPortable.exe can't work.

ERROR Log:
D:\PortableProgram\ClamWinPortable\App\clamwin\bin\ClamWin.exe.log

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Traceback (most recent call last):
File "ClamWin.py", line 28, in ?
File "RedirectStd.pyo", line 54, in ?
IOError: [Errno 2] No such file or directory: 'R:\\Local Settings\\Temp\\ClamWin1.log'

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