Chrome Resetting to Defaults

I've installed Chrome Portable on my USB drive and I thought all was well...

But it seems to be resetting back to defaults every couple of days. It will be working fine remembering recent tab, settings, passwords, etc.

Then it will open like it's never been run before. I will ask if it wants to be the default browser and all the other data is gone.

Any idea what might be going on? I really hate to lose my bookmarks, passwords, tabs, every couple of days.

Thanks in advance.