Program: Trillian
License: Free but not open source(Basic version)
Description: Universal Instant Messenger
Website: http://trillian.cc (official)
http://www.trilliananywhere.com/ (Trillian portable.)
Other: http://www.trilliananywhere.com/ has a step by step page on how to do that, but I found it would be much more conveniet if it were possible to make like Firefox portable, a patch on the original software.
It's already available for U3 technology, but I distrust U3 and I prefer to install it in some non U3 compatible devices such as network drive and/or convetional hard disks (with USB interface or Serial Ata drives)
Thanks guys, Portableapps is much better than U3 
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Both this and Total Commander have been discussed MANY times.
Sometimes, the impossible can become possible, if you're awesome!
Oops! My bad!
Trillian anywhere has issues as it still requires a drive letter in the path for its settings files.
If you want a portable Trillian that works very well.
Download Trillian for U3 and extract it.
Instructions Here
For those who have fought for it, freedom has a flavor the protected will never know.
"Because they stand on a wall and say, 'Nothing is going to hurt you tonight. Not on my watch.'" (A Few Good Men)
Coincidence is God's way of remaining anonymous.(Albert Einstein)
Or... you can just tell trillian to install itself to your pendrive's root folder. It seems (or it has worked for me) that trillian makes itself portable when installed on a portable device. I don't know if it will work for everyone, but it did for me. You might want to try it.
Thanks a lot for the tip. It helped me a lot.
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