Name: Seesmic
Website: http://seesmic.com/seesmic_desktop/sd2/
License: Freeware
Description: Follow your updates on multiple Twitter, Facebook and Linkedin accounts at the same time. Run searches, monitor userlists and share what you're doing to dozens of networks through Ping.fm. Use the smart account selection to manage your responses. Enable our desktop notifications to ensure that you don't miss a beat. All you need to effectively manage your major social networks is finally here with Seesmic Desktop 2.
Notes: There is a very handy web-based client that I currently use however I believe the desktop version would have more features.
EDIT: Request cancelled due to Adobe AIR dependency. Even if a lot of Keyboard Kung-Fu did make it possible to develop, I don't think AIR application would be good for PortableApps.com.
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As far as I know, Seesmic Desktop is not open source, and it runs on top of Adobe Air, is not a stand alone app.
If a packet hits a pocket on a socket on a port,
and the bus is interrupted as a very last resort,
and the address of the memory makes your floppy disk abort,
then the socket packet pocket has an error to report
I thought it was silverlight, which makes it even more of a mess
Too many lonely hearts in the real world
Too many bridges you can burn
Too many tables you can't turn
Don't wanna live my life in the real world