With notepad2-mod 4.2.25 r796, "file - create desktop link" creates a reference to the non portable executable.
Follows link contents:
C:\USB8\PortableApps\Notepad2-modPortable\App\Notepad2-mod\Notepad2.exe -n
"C:\Users\usuario\Google Drive\notas.txt"
Instead, I suposse that should be:
C:\USB8\PortableApps\Notepad2-modPortable\Notepad2-modPortable.exe -n
"C:\Users\usuario\Google Drive\notas.txt"
Like other functions within apps like registering file associations or starting with Windows, this function only applies to the local app and won't work with the portable one. It should not be used.
Sometimes, the impossible can become possible, if you're awesome!
OK -- Thanks for your advice.