With the standard Firefox you can create multiple profiles by using the command line or customized shortcut with the switch "/p", I believe. Is there a way to enable Portable FireFox to accomplish the same thing?
New: Kanri (Oct 9, '24), Platform 29.5.3 (Jun 27, '24)
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Second/Third Profile Support: https://portableapps.com/support/firefox_portable#second_profile
Firefox's profile manager does not support portable profiles, so we built our own easy way to do it.
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I am using the following FirefoxPortable.ini to allow for multiple instances. The issue is that this does not work using 2 portable versions of Firefox unless they are both full version. When opening the main portable profile and then opening a 2nd Profiles it results in the error another instances is running. If you open a 2nd Profile then the Main profile it will work. In short the "FirefoxPortable2ndProfile" does not recognize the .ini file.
[FirefoxPortable]
FirefoxDirectory=..\..\FirefoxPortable\App\firefox
ProfileDirectory=profile
SettingsDirectory=settings
PluginsDirectory=plugins
AdditionalParameters=
LocalHomepage=
WaitForFirefox=true
DisableSplashScreen=false
AllowMultipleInstances=true
DisableIntelligentStart=false
SkipCompregFix=false
RunLocally=false
# The above options are explained in the included readme.txt
# This INI file is an example only and is not used unless it is placed as described in the included readme.txt
This is the way Firefox itself is designed. You can't have the same copy of Firefox running two profiles at the same time. You can have different copies of Firefox running different profiles. Also note that this isn't really designed for production use and will have other side effects (like not being able to open clicked links from other apps).
Sometimes, the impossible can become possible, if you're awesome!