Indexing (X1, Copernic) Tbird mail in other than C\App data

I'm trying to justify moving from Outlook to Tbird but one the critical parts for me is quick and advanced search using X1 or Copernic. The only way I've gotten them to work is if Tbird leaves the mail in the typical install location. Does anyone know a work around or how to get these programs to index mail for a profile on a separate partition?
Thanks