What's HydraIRC?
What's Internet Relay Chat?
HydraIRC is an open-source IRC client with an attractive and easy to use interface. It supports DCC Chat and File transfers, Connecting to multiple servers, Dockable Floating Tabbed Windows, Autohiding Windows, DLL Plugins, Channel Monitoring, Message Logs, Event Viewer, Themes, Color schemes, Buddy groups, Audible and Visual Notifications , Reg-Exp Highlighting, Favorites and much more.
Note: HydraIRC is NOT a script, plugin or any other kind of add-on for mIRC. In fact it's got nothing to do with mIRC at all
This is an absolutely wonderful IRC client that I've been using for quite a while now. 
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ChatZilla for Firefox.
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R McCue
"If you're not part of the solution, you're part of the precipitate."
I've used it, but perhaps some people would prefer a separate application.