On your TB page it is said:
Sometimes, certain profiles will cause the launcher to fail or hang. In that case, start from scratch and try just copying your mailstores (Mail and ImapMail directories) as well as your prefs.js and abook.mab files. unquote
Installed and twice tried to open TB from the portable platform and it wouldn't go. Feared I would have to delete all and start over. However, quickly discovered that it would start if clicked on the TBPortable.exe. And thereafter it continues to start using the platform.