I think an anti-virus such as AVG free edition,AVG Anti-rootkit free,Avast! Home edition and a-squared 4.0 Free should be a portable app.
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Couple of problems with that:
1) None of those are open-source, right now, we only do open source apps.
2) We already have ClamWin, which is an AV
Use the search box! Please!
those programs are already portable in U3 format. they are closed souce and will not be hosted here.