Randomly losing data with Amsn portable.

hey there for some reason my amsn portable is randomly losing emotes and data even tho its in its data files. i often copy the app from the thumb drive to my desktop; when I'm using it at home then back because I like how its self contained and easy to back up. But sometimes emotes arent available and my font and settings and everything changes back to defaults for no reason even if it was on the hard drive at the time I'll reboot and all my settings will be gone. There seems to be no reason for it especially how I can see all my emotes in my profile folder but they wont show up in the emote browser or are usable in amns. How can I stop this happening? Thanks.