USBDriveFresher

I came across this program on Softpedia today. Looks interesting and I gave it a try. Worked decently well, too. Here's info:

The USBDriveFresher application will help you keep your USB drive clean by removing unwanted files automatically and according to rules you specify.

Your computer and others may automatically place files on your USB drive every time you use it. Now you can keep it clear and clean just as automatically – using rules you set up and approve.

USBDriveFresher is so handy you'll wonder how you ever got along without it. Every time you use your USB drive in a different computer you might see some little files/folders on your drive like thumbs.db, or .Trashes folder, or .Spotlight-V100, or the ones with the underscore at the start of the name. Using USBDriveFresher you'll never see those files again. It is designed to be a "Set it and forget" tool.

Here are some key features of "USBDriveFresher":
· Customizable cleanup patterns
· Predefined patterns
· Cleanup USB drive with a mouse click
· Autocleanup USB drive when it is plugged in
· Folder cleanup

Homepage
http://affinity-tools.com/usbfresher/