Pop-up blocker?

I hate asking at forum's that i'm not a long-time member, and it seems like i've already done it too much here. I'm just hoping you guys can help.

Basically there's a small story here. My sister's boss is having computer problems, some sort of adware problem(i won't know exactly what i'm dealing with until I get there) but i was sort of drafted against my will into taking a bit of a look at it. (to earn her some good points with her new boss)

there's a small problem though. The computer is suposed to have a bad popup issue. hopefully booting up in safemode will disable them but just in case i was wondering if there was a portable popup blocker?

Or failing that if you guys know of a way to disable popups long enough for scanners to be installed?

Sorry for causing any hassle. I'm kinda displeased about this myself.