This issue has been consolidated into this topic:
https://portableapps.com/node/22959
Today morning I would start PortableApps, but McAfee VirusScan reported virus alert at the PortableAppsPlatform.exe.
Name: F:\PortableApps\PortableApps.com\PortableAppsPlatform.exe
Virus: Artemis!0E1A49A03054
McAffee deleted the file.
McAffee DAT-Version: 5917.0000
Afer loading the new installation package from portableapps.com and reinstallation, I got the same problem after the installtion process.
Update:
After switching of the heuristic sensitivity of the access scan I got no more virus alert. It is an false positive message from VirusScan, I think.