Cannot delete some files on my Portable Apps USB.

My Opera folder on my Portable Apps USB seems to have become corrupted. When I open it the file structure is all messed up and the files names are a bunch of symbols and characters. All my other files and folders on the drive are fine and they run fine, it's just Opera that's messed up. It's not malware, I ran several scans on it.

The problem is I can't delete the Opera folder. I get a message about not recognizing the file structure or location doesn't exist. How can I delete the folder?