I have yet to try, as I'm worried about what could happen.
I want to use a Full Install of SeaMonkey at the same time as my Portable SeaMonkey- both open at the same time and being tweaked concurrently.
I tried a search, found nothing recent.
My reasons for this:
I want to make a 100% standard theme for SeaMonkey that I can use in my Portable Version. Eventually, I would like to approach somebody about including it somehow.
If nothing else, I would like to learn more from the experience about portablizing apps.
Thank you for any and all guidance on this!