I got a notice that an update for VLC was available today and I selected to have it installed.
The package v18.104.22.168 (according to header):
!define PORTABLEAPPNAME "VLC Media Player Portable"
!define APPNAME "VLC"
!define NAME "VLCPortable"
!define VER "22.214.171.124"
!define WEBSITE "PortableApps.com/VLCPortable"
!define DEFAULTEXE "vlc.exe"
!define DEFAULTAPPDIR "vlc"
!define DEFAULTSETTINGSDIR "settings"
!define LAUNCHERLANGUAGE "English"
Tries to install the file (:\PortableApps\VLCPortable\App\vlc\vlc-cache-gen.exe) which is infected with [MalCrypt.Indus!@105441913] for VLC version 2.1.2 payload.
I have raised the matter with Comodo to see if this is a false positive or not, but for now it should be noted that this warning is being issued.