I don't know if it's been done already but this type of tool would be handy to add to the library here... anybody know of one?
New: InnoUnpacker (Sep 17, 2025), Platform 30.1.1 (Nov 04, 2025)
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Though not exactly what you are talking about, using regshot before and after installing a program and before and after running it will get the information you need regarding portability.