Crazy idea that may make no sense or not even be feasible

Ok I know this sound far fetched but would be something that I was thinking of.

I have multiple USB sticks/hard drives with various setups of PortableApss on them Including one sitting on a 500gb external USB 3 Drive that pretty much is always plugged into to same computer.

So here is idea:
Would it be possible to write a script or external program that could be run independent of the platform that would read the database fo PortableApss file installed on device and update those if needed with out actually launching the specific Portables platform, having it a way to select the drive letter if it detected multiple instances of hte platform?

This would be as opposed to launching the platform, updating, closing platform, inserting next drive and repeating process all over again?

Doable? Usable? Too outrageous?Or am I even making self understandable?