Firefox suddenly fail to load config

My Portable Firefox has been working fine till today, it stops loading everything (add ons, history, cookies, storage, etc.), basically all profile.

When I try to login to the sync account, it says that cookies and storage have been disabled, but under privacy, everything is set to accept. Tried installing new copy. Still the same thing.

What had happened with my firefox? All I did last was just quit the app, and start today.

Help. Anyone?