Can U3 apps usable in portableapps.com?

I have been reading the forums a lot on how to get Skype working in portable apps, and actually had a U3 USB drive for about two weeks. (Bought it at OfficeMax and returned it two weeks later because I didn't like it. No problems.) And I see that Skype has a U3 application. So my question is, could a wrapper or launcher be written to allow U3 applications to work in portableapps.com. U3 claims to be a standard, so I don't think there is any copy infringments,
(And yes, I know that portableapps works much more efficiently, uses less space, and memory but until we can convince software makers to write for portableapps also, it would be a good stop-gap measure.)
Finally, I would like to add that I love portableapps. I have even went so far as to install the same apps (non-portable versions) on my home PC, both in Windows XP and Xubuntu, and set up my XP and Xubuntu structures so that I all my updated files can be transfured to the USB in one step. (I just don't usually have my USB HDD plugged in, and I switch between windows and linux.) Keep up the good work.