there is some errors in Laucher.ini in TheGuidePortable.the ini file has few lines of FileWrite to replace config item in %PAL:DataDir%\settings\guide.ini,like this
;[FileWrite1]
;Type=Replace
;File=%PAL:DataDir%\settings\guide.ini
;Find=%PAL:LastDrive%%PAL:LastPackagePartialDir%\
;Replace=%PAL:Drive%%PAL:PackagePartialDir%\
but with this ,the guide.ini file become erroable,the last item become
[Recent File List]
File1=PAL:PortableAppsBaseDir\PortableApps\TheGuidePortable\Data\theguide.gde
so,if TheGuide set to load last document, when it starts,it always say the gde file invalid.
after delete or comment the FileWrite# block in laucher.ini,always works fine.