May 4rd I had to reboot my Windows10 due to a system update on May 3rd and found that I suddenly couldn't launch several portable apps because they reported the following:
The application was unable to start correctly (0xc000007b). Click OK to close the application.
This only affected the launchers, if I tried the main executables, these would run without a problem.
Among the affected launchers were 7-Zip, Notepad++ and several others (didn't make notes of all of them but these two I use almost daily so they were the most important to me.)
I must assume something in the Windows update messed things up because after using System Restore to go back to just prior to this update, the error didn't occur and all of the launchers worked again.
Since I'm not exactly thrilled to go through this again I've paused Windows Update (says it resumes on 6/10/2019) and only hope I can pause it again if the cause (be it the update or something in the way these launchers were build) isn't found before this time.