I have a 1 TB USB Drive which I use reasonably regularly.
My PC is a Win 10 HP computer 64 bit, a few years old.
Now when Portable Apps opens it minimises after saying "file access denied".
At the same time it does call and install updates.
Can anyone please help??
Bugs must be reproducible..
When the issue is related to a computer (or its related OS), it won't be easy to re-simulate the same bug.
Try making basic tests, like using another drive/computer, etc.
Illusions are an infinite paradise.
What filesystem is the drive formatted to?
If it is NTFS there may of been an update that sets access permissions on NTFS drives.
Or your Anti-Virus may be interfering (false positive or otherwise)
More details will help others to be able to help you.