Apps won't run

I installed PortableApps to a USB flash drive and downloaded a few apps. Whenever I try to run an app I get the User Account Control message, "Do you want to allow this app to make changes to your device?" I then select "Yes", the message disappears like normal, but then nothing happens. I've tried selecting "No" and also "run as an administrator" but those didn't make a difference either.

I'm running Windows 10 Home, Version 21H2 (Build 19044, 1889)

Has anyone run into this before?