Hi,
Here's my problem : my computer crashed, PortableApps.com Opera Portable Edition was running.
When I restarted and tried to lauch it again, I got the error box :
"Une autre instance de Opera, Portable Edition est déjà en cours d'exécution. Veuillez fermer les autres instances de Opera, Portable Edition avant de lancer Opera, Portable Edition."
Problem is : there is no other instance running !
I tried to restore backups : I get the same error message on THIS computer but it works fine on another.
I really don't know what to do 
Any help would be welcome.
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another instance of Opera is already running
December 17, 2022 - 5:25am
#1
another instance of Opera is already running
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If you open up task manager to the full process view, can you ensure there's no OperaPortable.exe running? If you try a temporary fresh install to your Desktop, does it work there?
The issue here is that it's using a Windows API to OpenMutex and CreateMutex to ensure it's not running. If Windows hard crashes and messes up some of its own files, it can impact this feature. I recall it happening to someone after a virus infection and it required either a Windows reinstall or restoring to a Restore Point.
Sometimes, the impossible can become possible, if you're awesome!
Thanks for coming back to me I was a bit desperate !
OK, checked task manager (after a few restarts that was highly improbable, but then... » same
Fresh install on the desktop » same
A few system checks (checked registry, checked every drive, ran an sfc /scannow that repared a few problems) » same
I had to restore my computer to before the crash (thankfully, I have a full daily backup of the system) and guess what, that solved it.
Not sure if restoring to a Restore Point would have been enough, but that would be the first thing to try (if you have one).
Thanks for the support.
Daniel