After succesfull install of last version Potplayer (PotPlayerPortable_1.7.21953.paf.exe) there is not posible run this program - it stop running with message window "Error: PotPlayer.dll is modified or hacked..."
Same behaviour on two different PCs, after fresh install...
https://portableapps.com/comment/254959#comment-254959
It's maybe your Antivirus, some altered files, etc.
Maybe an OS or Hardware related issue! Read this to get more ideas of how to retrace it.
'Words are merely the coverings of consciousness'
― Neo Buddha ―