Firefox 144.0.2, various sites not loading.

I've just upgraded to Firefox 144.0.2 from 140.0.4.

Whereas 140.0.4 is working fine, since upgrading there are various sites not loading such as Facebook and Virus total.

Starting with 141.0.3 the web pages are not loading.

Any thoughts on this please? I've tried adjusting various setting but I'm having no luck.
Consequentially I'm having to run the older version

Thanks