Bookmarks mapping for flash drive changes

Bookmarks mapping for flash drive changes
at home and for it's portability purpose away from home.

At home the range is usually somewhere between D: and H:
and away from home the range is going to be greater. In
any case it would affect all of the following:

1) home page whether my file or the help file in portablefirefox

2) location of the profile directory in a keyword shortcuts (shortcuturl=)

3) working files on c: at home or copied versions on flash
drive away from home accessed from keyword shortcuts.

4) .BAT file used to copy from home computer to the
flash drive using the same directory names and structure.

5) .BAT file used to copy the home computer profile to
to the portable device

So the question is how can I make all the above work,
without manually making major changes.

Incidentally I have over 100 bookmark references to my c: drive and I
think they would almost all be keyword shortcuts that
would be involved on a portable drive, if I carried my
files with me for reference not necessarily for updating.