If so, can you check your FF profile dir? Mine gains lots of temp files FF is NOT cleaning up. Shutting down Avast! stops this, but I am also running U3 launcher and even corporate-mandated MicroTrend on my host, so just need to know if these are relevant details or not.
Directory of F:\PortableApps\FirefoxPortable\Data\profile
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11/21/2006 08:39 AM 185,597 bookmarks-1.html
11/21/2006 08:39 AM 185,597 bookmarks-2.html
11/21/2006 08:39 AM 185,593 bookmarks-3.html
11/21/2006 08:39 AM 185,597 bookmarks-4.html
11/21/2006 08:39 AM 185,597 bookmarks-5.html
11/21/2006 08:39 AM 185,597 bookmarks-6.html
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11/21/2006 09:28 AM 5,809 sessionstore-1.js
11/21/2006 09:37 AM 5,323 sessionstore-2.js
11/21/2006 09:38 AM 6,569 sessionstore-3.js
11/21/2006 09:42 AM 14,517 sessionstore-4.js