App sometimes does not open on Windows 10

Hi masters,

For some reason the PortableApps I have on OneDrive just does not open. I try to execute Start.exe and no process is generated.
When I restart the computer it works fine for some days.
But, if I try to open it though PortableApps\PortableApps.com\PortableAppsPlatform.exe it always works fine.
Please, someone have any clue of whats going wrong here?

Thanks a lot and regards