So the most likely options are that either your virus definitions are out of date, or you have picked up malware from somewhere else that has infected Qmmp.
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Our installer for 1.6.4 is fine, which you can see here on VirusTotal.
So the most likely options are that either your virus definitions are out of date, or you have picked up malware from somewhere else that has infected Qmmp.
Upon attempting to copy the program from one drive to another ESET caught it as Malware. De-installed and the problem is no more.
Thanks,
RAH