Firefox Portable + javascript enabled = weird Digg problem

I have been experiencing some problems lately with Firefox portable while visiting Digg.com. I've narrowed the problem down to javascript being enabled or disabled. When it's disabled, Digg works just fine. When javascript is enabled, with all sub-options unchecked, and I click on a story, a new tab will open up, but the article that I was trying to read doesn't come up. Instead, I get the Digg "Opps, the page you are trying to find cannot be found" page. The weird thing is that in the address bar, the URL of the website that I was trying to go to is there. Anyone else had this problem? Is it something with the cache? Or maybe it has to do with opening the articles in a new tab?? Any insight would be greatly appreciated. I hate having to fall back to Internet Exploder.

Thanks,
Anderson