Portable GIMP 2.2.12 has been working well on my Windows XP machine. Today when starting the program, Panda Internet Security 2005 Platinum popped up a dialog reporting that it had neutralized spyware. Portable GIMP then stopped loading with a dialog reporting "gimp-2.2.exe - Unable To Locate Component" in the title bar, "This application has failed to start because intl.dll was not found. Re-installing the application may fix this problem." in the text portion of the dialog.
The Panda popup says the adware it neutralized was "Adware/DesktopMedia" in the location "...\temp\nspf.temp\system.dll"
The Panda page provided for additional information is at this address:
and indicates that detection of this adware was last updated Oct. 10, 2006, exactly the same day my Portable GIMP stopped working.