How To Replace the U3 Software on a U3 Enabled device
First and foremost you need to decide what you want to replace your U3 software with. there are several programs that can run a file on a different drive, but the one i find is MOST user friendly is an Open Source Program Called u3-Autorun not only is it lightweight it will also let you run ANY program that you want by simply changing the proper line in the u3-autorun.ini that you place on the root of your drive.